Editorial
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Received: 2022-04-24 | Revised:2022-04-27 | Accepted: 2022-04-27 | Published: 2022-04-27
Pages: 1-2
DOI: https://doi.org/10.56717/jpp.2022.v01i01.001
Abstract
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Abstract Keywords
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Journal of Phytomoleculs
& Pharmacology: ‘Why a new journal?’
Because around 80% of registered medications come from plants
or were inspired by natural products.’ In other words, nature is still the best
organic chemistry laboratory, and to cure ourselves we must safeguard the Earth
biological diversity. Biodiversity and human health are interconnected in
various ways, including food and water security, sustainable agriculture,
ecosystem resilience, climate change mitigation and, not least, drug discovery.
Indeed, plant and microbial diversity has been an irreplaceable resource of
active ingredients for medicines and health products. Hundreds of thousands of
plant species populate the planet, of which only a fraction has been
investigated for their pharmacologic potential. These limitless and still
largely unexplored natural resources have been used extensively for healing
practices throughout human history and across cultures. Such valuable
traditional knowledge is often specific to particular human groups living in
specific environments and is usually passed down from generation to generation
with a long history of use in maintaining health and preventing and treating
disease. In this context, great importance should be given to bioprospecting
(also known as biodiversity prospecting), i.e., the exploration, extraction and
screening of biological diversity and indigenous knowledge for the search for
natural products from plants, fungi and microorganisms to develop commercially
valuable products for pharmaceutical, agricultural, nutritional, cosmetic and
other applications (Convention on Biological
Diversity, UNEP/CBD/COP/5/INF/7) [1].
However, the appropriation of biological resource and traditional
knowledge must be ethical, lawful and not incur biological theft and biopiracy.
In other words, the dependence on biodiversity for new drugs continues today in
almost all areas of medicine. Not less important, combining natural products
(i.e., plant extracts, phytochemicals, or essential oils) with conventional
drugs offers another field of application and should be pursued extensively.
This has been previously investigated with natural products used in combination
with anticancer drugs and antimicrobials. This therapeutic approach can
chemosensitize chemoresistant cancer cells, fungi and bacterial strains by, for
instance, inhibiting the cellular active efflux system, a conserved drug
resistance mechanism that pumps xenobiotics out of the cell [2-12].
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Received: 24 April,
2022
Revised:
27
April, 2022
Accepted: 27 April, 2022
Published: 27 April, 2022
This work is licensed under the
Creative Commons Attribution
4.0
License (CC BY-NC 4.0).
Abstract
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Abstract Keywords
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This work is licensed under the
Creative Commons Attribution
4.0
License (CC BY-NC 4.0).
Editor-in-Chief
This work is licensed under the
Creative Commons Attribution 4.0
License.(CC BY-NC 4.0).