Journal of Phytomolecules & Pharmacology
The Journal of
Phytomolecules & Pharmacology (JPP) is a
peer-reviewed international journal that brings out original research papers,
reviews and short communications on the natural product & derivatives,
phytoconstituents, biological & pharmacological investigations of the
extracts and products.
The journal specifically invites
interdisciplinary articles on phytochemistry, biotechnological approach for
phytomedicines, biological and toxicological mechanisms of action, structure
and bioactivity of phytochemicals (bioinformatics/ computational methods).
Moreover, JPP emphasizes the
fascinating insights of ethnic medicines involved in tribal communities.
Therefore, we particularly prefer scientific investigations on either
pharmacological or phytochemical aspects of the medicinal, aromatic, economical
plants and other related botanically species, fungi as well as organisms.
Manuscripts dealing with significant new findings on the plant's phytochemistry
and pharmacological experiment for drug discovery will be considered.
The journal operates a double-blind
peer review policy. All articles will be made freely and permanently available
in online. Articles are published as “Just Accepted Articles” as soon as
possible after acceptance and in 2 issues of a volume per year.
Optimizing the extraction of berberine from the stem of Tinospora sinensis (Lour.) Merr by response surface methodology
Nhung Vu Thi Tuyet*
Nhung Vu Thi Tuyet*
Corresponding
Author
Institute
of Life Science, Vietnam Academy of Science and Technology, Ho Chi Minh
city, Vietnam.
Email: vttnhung@ils.vast.vn, Tel: +84 982 925 298
Nguyen Hoang Trung
Nguyen Hoang Trung
Institute of Life
Science, Vietnam Academy of Science and Technology, Ho Chi Minh city, Vietnam.
E-mail: nguyentran1944@gmail.com
Dung Hoang Nguyen
Dung Hoang Nguyen
Institute of Life
Science, Vietnam Academy of Science and Technology, Ho Chi Minh city, Vietnam.
E-mail: nhdung@ils.vast.vn
Loan Le Quynh
Loan Le Quynh
Institute of Life
Science, Vietnam Academy of Science and Technology, Ho Chi Minh city, Vietnam.
E-mail: lqloan@ils.vast.vn
Ngoc Tran Thi My
Ngoc Tran Thi My
Institute of Life
Science, Vietnam Academy of Science and Technology, Ho Chi Minh city, Vietnam.
E-mail: ngocmy178@gmail.com
Dao Duong Thi Hong
Dao Duong Thi Hong
Institute of Life
Science, Vietnam Academy of Science and Technology, Ho Chi Minh city, Vietnam.
E-mail: duonghongdao160695@gmail.com
Thao Nguyen Thi Thu
Thao Nguyen Thi Thu
Institute of Life
Science, Vietnam Academy of Science and Technology city, Ho Chi Minh, Vietnam.
E-mail: nguyenthithuthao29011998@gmail.com
Kien Tran Trung
Kien Tran Trung
Institute of Life
Science, Vietnam Academy of Science and Technology, Ho Chi Minh city, Vietnam.
E-mail: trkientr@yahoo.com
Received: 2025-04-29 | Revised:2025-05-14 | Accepted: 2025-05-14 | Published: 2025-05-19
Pages: 50-60
127 Views | 127 Download
Ethyl acetate fraction of Diaphananthe bidens leaf extract showed immunomodulatory activity in experimental mice models
Mba Ogbonnaya*
Mba Ogbonnaya*
Corresponding
Author
Department
of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, Nnamdi
Azikiwe University, Awka, Nigeria.
E-mail: mbabte@gmail.com, Tel: +2348115148593
Ikechukwu Sonne Mbagwu
Ikechukwu Sonne Mbagwu
Department
of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, Nnamdi
Azikiwe University, Awka, Nigeria.
E-mail:
is.mbagwu@unizik.edu.ng
Ernest Chima Orji
Ernest Chima Orji
Department
of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, Nnamdi
Azikiwe University, Awka, Nigeria.
E-mail: ec.orji@unizik.edu.ng
Harrison Uchechkwu Orji
Harrison Uchechkwu Orji
Department
of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, Nnamdi
Azikiwe University, Awka, Nigeria.
E-mail: hu.orji@unizik.edu.ng
Daniel Lotanna Ajaghaku
Daniel Lotanna Ajaghaku
Department
of Pharmacology, Faculty of Pharmaceutical Sciences, Enugu State University of
Science and Technology (ESUT), Enugu, Nigeria.
E-mail: daniel.ajaghaku@esut.edu.ng
Received: 2025-04-09 | Revised:2025-04-26 | Accepted: 2025-04-29 | Published: 2025-05-11
Pages: 39-49
127 Views | 127 Download
Therapeutic potential of anti-cancer compounds from African medicinal plants: From in vitro studies to clinical applications
Chukwuemeka Augustine Nwachuya*
Chukwuemeka Augustine Nwachuya*
Corresponding Author
Department of
Pharmacology & Toxicology, Faculty of Pharmaceutical Sciences, University
of Nigeria, Nsukka, Nigeria.
E-mail: nwachuyachukwuemeka.cn@gmail.com, Tel: +2308131655482
Obinna Patrick Eche
Obinna Patrick Eche
Department of Microbiology, University of Georgia, Athens.
E-mail: oeche06@outlook.com
Amauche Pearl Ngige
Amauche Pearl Ngige
Department of Clinical Pharmacy and Pharmacy Management, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria.
E-mail: ngigepearl@gmail.com
Abdulmuminu Isah
Abdulmuminu Isah
Department of
Clinical Pharmacy and Pharmacy Management, Faculty of Pharmaceutical Sciences,
University of Nigeria, Nsukka, Nigeria.
E-mail: abdulmuminu.isah@unn.edu.ng
Chukwuemeka Sylvester Nworu
Chukwuemeka Sylvester Nworu
Department of
Pharmacology & Toxicology, Faculty of Pharmaceutical Sciences, University
of Nigeria, Nsukka, Nigeria.
E-mail: chukwuemeka.nworu@unn.edu.ng
Received: 2025-03-13 | Revised:2025-04-20 | Accepted: 2025-04-22 | Published: 2025-04-30
Pages: 20-38
127 Views | 127 Download
Effect of extraction solvents on total polyphenolic content, total flavonoid content, and antioxidant activity of Tunisian cultivated mulberry (Morus alba L.) fruit extracts
Amel Azaza
Amel Azaza
Laboratory of Biotechnology and Biomonitoring of the Environment and Oasis Ecosystems (LR21ES26), University of Gafsa, Faculty of Sciences of Gafsa, Department of Life Sciences, University Campus, Sidi Ahmed Zarroug, Gafsa, Tunisia.
E-mail: amel2azeza@gmail.com
Ines Taieb
Ines Taieb
Laboratory of Analysis, Treatment and Valorization of the Pollutants of the Environment and Products, Faculty of Pharmacy, University of Monastir. Avicenne Street, Monastir 5000, Tunisia.
E-mail: ines.taieb@isbm.u-monastir.tn
Farah Zidi
Farah Zidi
Department of Life Sciences, Faculty of Sciences of Gafsa, University Campus Sidi Ahmed Zarroug, University of Gafsa, Gafsa 2112, Tunisia.
Abdallah Fraj
Abdallah Fraj
Department of Life Sciences, Faculty of Sciences of Gafsa, University Campus Sidi Ahmed Zarroug, University of Gafsa, Gafsa 2112, Tunisia.
E-mail: frajabd@gmail.com
Ramzi Amari
Ramzi Amari
Department of Life Sciences, Faculty of Sciences of Gafsa, University Campus Sidi Ahmed Zarroug, University of Gafsa, Gafsa 2112, Tunisia.
E-mail: ramziamari@yahoo.fr
Monia Bendhifi-Zarroug
Monia Bendhifi-Zarroug
Monia
Bendhifi-Zarroug
Department
of Life Sciences, Faculty of Sciences of Gafsa, University Campus Sidi
Ahmed Zarroug, University of Gafsa, Gafsa 2112, Tunisia.
And
Biodiversity,
Biotechnology and Climate Change Laboratory (LR11ES09), Department of Life
Sciences, Faculty of Science of Tunis, University of Tunis El Manar, Tunis
2092, Tunisia.
E-mail: moniazarroug@gmail.com
Sami Souid
Sami Souid
Laboratory of Biotechnology and Biomonitoring of the Environment and Oasis Ecosystems (LR21ES26), University of Gafsa, Faculty of Sciences of Gafsa, Department of Life Sciences, University Campus, Sidi Ahmed Zarroug, Gafsa, Tunisia.
E-mail: sami_souid@yahoo.fr
Kheiria Hcini*
Kheiria Hcini*
Corresponding
Author
Department
of Life Sciences, Faculty of Sciences of Gafsa, University Campus Sidi
Ahmed Zarroug, University of Gafsa, Gafsa 2112, Tunisia.
And
Biodiversity,
Biotechnology and Climate Change Laboratory (LR11ES09), Department of Life
Sciences, Faculty of Science of Tunis, University of Tunis El Manar, Tunis
2092, Tunisia.
E-mail: hcinikheiria@yahoo.fr, Tel: +00216 49491686
Received: 2025-03-27 | Revised:2025-04-13 | Accepted: 2025-04-14 | Published: 2025-04-25
Pages: 13-19
127 Views | 127 Download
Influence of extraction solvents on total phenolic content and antioxidant activity of Tunisian Thymbra capitata (L.) Cav. aerial parts extracts
Ines Taieb
Ines Taieb
Laboratory of Analysis, Treatment and Valorization of the Pollutants of the Environment and Products, Faculty of Pharmacy, University of Monastir. Avicenne Street, Monastir 5000, Tunisia. E-mail: ines.taieb@isbm.u-monastir.tn
Amel Azaza
Amel Azaza
Laboratory of Biotechnology and Biomonitoring of the Environment and Oasis Ecosystems (LR21ES26), University of Gafsa, Faculty of Sciences of Gafsa, Department of Life Sciences, University Campus, Sidi Ahmed Zarroug, Gafsa, Tunisia.
E-mail: amel2azeza@gmail.com
Farah Zidi
Farah Zidi
Department of Life Sciences, Faculty of Sciences of Gafsa, University Campus Sidi Ahmed Zarroug, University of Gafsa, Gafsa 2112, Tunisia.
Abdallah Fraj
Abdallah Fraj
Department of Life Sciences, Faculty of Sciences of Gafsa, University Campus Sidi Ahmed Zarroug, University of Gafsa, Gafsa 2112, Tunisia.
E-mail: frajabd@gmail.com,
Ramzi Amari
Ramzi Amari
Department of Life Sciences, Faculty of Sciences of Gafsa, University Campus Sidi Ahmed Zarroug, University of Gafsa, Gafsa 2112, Tunisia. E-mail: ramziamari@yahoo.fr
Monia Bendhifi-Zarroug
Monia Bendhifi-Zarroug
Biodiversity, Biotechnology and Climate Change Laboratory (LR11ES09), Department of Life Sciences, Faculty of Science of Tunis, University of Tunis El Manar, 2092, Tunisia.
Sondes Stambouli- Essassi
Sondes Stambouli- Essassi
Biodiversity, Biotechnology and Climate Change Laboratory (LR11ES09), Department of Life Sciences, Faculty of Science of Tunis, University of Tunis El Manar, 2092, Tunisia.
E-mail: sondes.stambouli@fst.utm.tn
Kheiria Hcini*
Kheiria Hcini*
Corresponding Author
Biodiversity,
Biotechnology and Climate Change Laboratory (LR11ES09), Department of Life
Sciences, Faculty of Science of Tunis, University of Tunis El Manar, Tunis
2092, Tunisia.
And
Department of
Life Sciences, Faculty of Sciences of Gafsa, University Campus Sidi Ahmed
Zarroug, University of Gafsa, Gafsa 2112, Tunisia.
E-mail:
hcinikheiria@yahoo.fr, Tel: +00216 49491686
Received: 2025-03-06 | Revised:2025-03-24 | Accepted: 2025-03-24 | Published: 2025-04-23
Pages: 7-12
127 Views | 127 Download
A comparative study of total polyphenolic content and antioxidant activity of prickly Pear (Opuntia ficus-indica L.) seeds extract
Kheiria Hcini*
Kheiria Hcini*
Corresponding Author
Biodiversity,
Biotechnology and Climate Change Laboratory (LR11ES09), Department of Life
Sciences, Faculty of Science of Tunis, University of Tunis El Manar, 2092,
Tunisia.
And
Department
of Life Sciences, Faculty of Sciences of Gafsa, University Campus Sidi Ahmed
Zarroug, University of Gafsa, Gafsa 2112, Tunisia.
E-mail:
hcinikheiria@yahoo.fr, Tel:
+00216 49491686
Hayet Saoudi
Hayet Saoudi
Department of Life Sciences, Faculty of Sciences of Gafsa, University Campus Sidi Ahmed Zarroug, University of Gafsa, Gafsa 2112, Tunisia.
E-mail: saoudihayet123@gmail.com
Ines Taieb
Ines Taieb
Laboratory of Analysis, Treatment and Valorization of the Pollutants of the Environment and Products, Faculty of Pharmacy, University of Monastir, 5000, Tunisia.
E-mail: taibines@live.fr
Amel Azaza
Amel Azaza
Department
of Life Sciences, Faculty of Sciences of Gafsa, University Campus Sidi Ahmed
Zarroug, University of Gafsa, Gafsa 2112, Tunisia.
E-mail:
amel2azeza@gmail.com
Farah Zidi
Farah Zidi
Department of Life Sciences, Faculty of Sciences of Gafsa, University Campus Sidi Ahmed Zarroug, University of Gafsa, Gafsa 2112, Tunisia.
E-mail: farahzidi5@gmail.com
Monia Bendhifi-Zarroug
Monia Bendhifi-Zarroug
Biodiversity,
Biotechnology and Climate Change Laboratory (LR11ES09), Department of Life
Sciences, Faculty of Science of Tunis, University of Tunis El Manar, 2092,
Tunisia.
And
Department
of Life Sciences, Faculty of Sciences of Gafsa, University Campus Sidi Ahmed
Zarroug, University of Gafsa, Gafsa 2112, Tunisia.
E-mail:
moniazarroug@gmail.com
Abdallah Fraj
Abdallah Fraj
Department
of Life Sciences, Faculty of Sciences of Gafsa, University Campus Sidi Ahmed
Zarroug, University of Gafsa, Gafsa 2112, Tunisia.
E-mail: frajabd@gmail.com
Samiha Kahlaoui
Samiha Kahlaoui
Biodiversity,
Biotechnology and Climate Change Laboratory (LR11ES09), Department of Life
Sciences, Faculty of Science of Tunis, University of Tunis El Manar, 2092,
Tunisia.
E-mail:
sameh_kahlaoui@yahoo.fr
Sondes Stambouli-Essassi
Sondes Stambouli-Essassi
Biodiversity,
Biotechnology and Climate Change Laboratory (LR11ES09), Department of Life
Sciences, Faculty of Science of Tunis, University of Tunis El Manar, 2092,
Tunisia.
E-mail:
sondes.stambouli@fst.utm.tn
Received: 2025-02-16 | Revised:2025-02-22 | Accepted: 2025-02-24 | Published: 2025-03-05
Pages: 01-06
127 Views | 127 Download
Anti-wood-degrading fungi activity of triterpenes and sterols from Alstonia boonei stem bark
John Vershima, Anyam
John Vershima, Anyam
Centre
for African Medicinal Plants Research, North-Eastern University Gombe, Nigeria.
And
Department
of Chemistry, College of Physical Sciences, Joseph Sarwuan Tarka University,
Makurdi, Nigeria.
E-mail:
johnversh@gmail.com
David Oriabure Ekhuemelo*
David Oriabure Ekhuemelo*
Corresponding
Author
Department
of Forest Production and Products, Federal University of Agriculture Makurdi
(Now Joseph Sarwuan Tarka University, Makurdi) Nigeria.
E-mail: ekhuemelo.david@uam.edu.ng, doekhuemelo@yahoo.com, Tel: +234-703 133 2803
Terzungwe Atondo
Terzungwe Atondo
Department
of Forest Production and Products, Federal University of Agriculture Makurdi
(Now Joseph Sarwuan Tarka University, Makurdi) Nigeria.
Chigoziri Ekhuemelo
Chigoziri Ekhuemelo
Department
of Crop and Environmental Protection, College of Agronomy, Federal University
of Agriculture Makurdi. (Now Joseph Sarwuan Tarka University, Makurdi) Nigeria.
Received: 2024-11-27 | Revised:2025-01-04 | Accepted: 2025-01-06 | Published: 2025-01-06
Pages: 119-131
127 Views | 82 Download
Phytochemical content, antioxidant and antidiabetic activities variations in pre- and post-harvest conditions for the Cnidoscolus chayamansa McVaugh leaf
Cletus Anes Ukwubile*
Cletus Anes Ukwubile*
Corresponding
Author
Department of Pharmacognosy, Faculty of
Pharmacy, University of Maiduguri, Nigeria.
E-mail: caukwubile@unimaid.edu.ng, Tel: +238036985667
Hassan Braimah Yesufu
Hassan Braimah Yesufu
Department of Pharmaceutical Chemistry,
Faculty of Pharmacy, University of Maiduguri, Nigeria.
Matthew Onyema Agu
Matthew Onyema Agu
Department of Pure and Industrial
Chemistry, Nnamdi Azikiwe University Awka, Nigeria.
Received: 2024-12-10 | Revised:2024-12-24 | Accepted: 2024-12-24 | Published: 2024-12-27
Pages: 100-118
127 Views | 70 Download
Isolation, characterization and antibacterial evaluation of stem bark of Alstonia boonei (De Wild) (Apocynaceae) against selected wood associated bacteria
David Oriabure Ekhuemelo*
David Oriabure Ekhuemelo*
Corresponding
Author
Department
of Forest Production and Products, Federal University of Agriculture Makurdi
(Now Joseph Sarwuan Tarka University, Makurdi) Nigeria.
E-mail: ekhuemelo.david@uam.edu.ng,
Tel: +234-703 133 2803
Terzungwe Atondo
Terzungwe Atondo
Department of Forest Production and
Products, Federal University of Agriculture Makurdi (Now Joseph Sarwuan Tarka
University, Makurdi) Nigeria.
Emmanuel Terzungwe Tembe
Emmanuel Terzungwe Tembe
Department of Forest Production and
Products, Federal University of Agriculture Makurdi (Now Joseph Sarwuan Tarka
University, Makurdi) Nigeria.
Received: 2024-11-25 | Revised:2024-12-15 | Accepted: 2024-12-17 | Published: 2024-12-27
Pages: 87-99
127 Views | 85 Download
Evaluation of aqueous extracts of Musa acuminata (Banana) peels on the liver of streptozotocin induced diabetic Wistar rats
Sharon Kaundu
Sharon Kaundu
Department of
Human Anatomy, School of Medicine and Health Sciences, Mulungushi University,
Livingstone Campus, Zambia.
And
Department of
Clinical sciences, School of Medicine, Eden University, Lusaka, Zambia.
And
Department of Clinical sciences, School of Medicine, Eden University, Lusaka, Zambia.
Kombe Mwitwa
Kombe Mwitwa
Department
of Human Anatomy, School of Medicine and Health Sciences, Mulungushi
University, Livingstone Campus, Zambia.
And
Department
of Clinical sciences, School of Medicine, Eden University, Lusaka, Zambia.
Lukundo Mulambia Siame
Lukundo Mulambia Siame
Department
of Human Anatomy, School of Medicine and Health Sciences, Mulungushi
University, Livingstone Campus, Zambia.
Isabel Namfukwe Luambia
Isabel Namfukwe Luambia
Department
of Human Anatomy, School of Medicine and Health Sciences, Mulungushi
University, Livingstone Campus, Zambia.
Ally Siabwacha
Ally Siabwacha
Department
of Human Anatomy, School of Medicine and Health Sciences, Mulungushi
University, Livingstone Campus, Zambia.
Uthman Ademola Yusuf*
Uthman Ademola Yusuf*
Corresponding
Author
Department of Human Anatomy, School of
Medicine and Health Sciences, Mulungushi University, Livingstone Campus,
Zambia.
E-mail: uthmanademola@yahoo.com, uademola@gmail.com,
Tel: +260967682170
Department of Human Anatomy, School of Medicine and Health Sciences, Mulungushi University, Livingstone Campus, Zambia.
E-mail: uthmanademola@yahoo.com, uademola@gmail.com, Tel: +260967682170
Received: 2024-12-03 | Revised:2024-12-22 | Accepted: 2024-12-23 | Published: 2024-12-27
Pages: 73-86
127 Views | 83 Download
Editor-in-Chief
This work is licensed under the
Creative Commons Attribution 4.0
License.(CC BY-NC 4.0).